Pharmacognostical studies and evaluation of anti-inflammatory activity of <i>Ficus bengalensis</i> linn

Abstract

Pharmacognostical parameters for the leaves of Ficus bengalensis were studied with the aim of drawing the pharmacopoeial standards for this species: macroscopical and microscopical characters, physio-chemical constants, extractive values with different solvents, s uorescence analysis of dry powder, its reaction after treatment with chemical reagents under visible light, and UV light at 254 nm and 366 nm. Preliminary phytochemical studies on the Ficus bengalensis leaves were conducted. The determination of these characters will aid future investigators in their pharmacological analyses of this species. The anti-ins ammatory effect of ethanolic and petroleum ether extracts of fi cus bengalensis were evaluated in experimental animals. We have determined the anti-ins ammatory activity of ethanolic and petroleum ether extracts of the bark of Ficus bengalensis by oral administration of doses of 300 and 600 mg/kg/day of body weight to healthy animals. The extracts were studied for their anti-ins ammatory activity in carrageenan-induced hind paw edema in rats and the paw volume was measured plethysmometrically at 0 3h after injection. The ethanolic and petroleum ether extracts of Ficus bengalensis , signiÞ cantly reduced (P Ficus bengalensis exhibited more signiÞ cant activity than petroleum ether in the treatment of ins ammation. Key words: Ficus bengalensis , moraceae, vada, ins ammation, pharmacognostical, indomethacin.