TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Leif W. Ellisen, Jeffrey Bird, Daniel C. West, +4

Cell

ChromatinCell LineageDevelopmental BiologyGeneticsChromosomal Translocations +7

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan

Nature

Signal TransductionSignaling PathwayCell InteractionNotch-1 SignallingCellular Biochemistry +4

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat, +3

Nature

Developmental BiologySignal TransductionSignaling PathwayMolecular RegulationCellular Regulatory Mechanism +6

A Novel Proteolytic Cleavage Involved in Notch Signaling

Christel Brou, Frédérique Logeat, Neetu Gupta, +7

Molecular Cell

Protein FunctionSignal TransductionSignaling PathwayReceptor Tyrosine KinaseCellular Biochemistry +4

A Ligand-Induced Extracellular Cleavage Regulates γ-Secretase-like Proteolytic Activation of Notch1

Jeff S. Mumm, Eric H. Schroeter, Meera Saxena, +5

Molecular Cell

Protein FunctionSignal TransductionSignaling PathwayMolecular RegulationNatural Sciences +8

Fringe is a glycosyltransferase that modifies Notch

Daniel J. Moloney, Vladislav M. Panin, Stuart H. Johnston, +8

Nature

Natural SciencesGlycobiologyBiochemical GeneticsMolecular BiologyMorphogenesis +4

Mind Bomb Is a Ubiquitin Ligase that Is Essential for Efficient Activation of Notch Signaling by Delta

Motoyuki Itoh, Cheol‐Hee Kim, Gregory R. Palardy, +11

Developmental Cell

Signal TransductionSignaling PathwayCell RegulationMedicineNatural Sciences +8

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

Michelle S. Rhyu, Lily Yeh Jan, Yuh Nung Jan

Cell

Developmental BiologyCell DivisionNumb ProteinAsymmetric DistributionCell Fate Determination +6

The Notch1 receptor is cleaved constitutively by a furin-like convertase

Frédérique Logeat, Christine Bessia, Christel Brou, +4

Proceedings of the National Academy of Sciences

Glycosyltransferase activity of Fringe modulates Notch–Delta interactions

Katja Brückner, Lídia Pérez, Henrik Clausen, +1

Nature

Signal TransductionGlycosyltransferase ActivityBiochemistryMolecular RegulationNatural Sciences +6