Publication | Closed Access
Electrically Controlled Drug Delivery from Biotin‐Doped Conductive Polypyrrole
318
Citations
24
References
2006
Year
EngineeringSmart PolymerBiofabricationBiomedical EngineeringPolymersConducting PolymerPharmaceutical TechnologyDrug Delivery SystemPolymer ChemistryStreptavidin LinkerMolecular EngineeringPharmacologyControlled Drug DeliveryRelease MechanismBiofunctional MaterialPolymer-drug ConjugateNerve Growth FactorDrug Delivery SystemsMedicineDrug Discovery
A platform for controlled drug delivery using a conductive-polymer substrate has been created. Through the incorporation of biotin into the conductive polymer polypyrrole (PPy) and the subsequent attachment of the desired drug molecule (such as nerve growth factor, NGF) via a streptavidin linker, an applied potential can trigger release of the drug from the polymer surface (see figure).
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