Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

Alan Daugherty, J. Lawrence Dunn, Debra L. Rateri, +1

Journal of Clinical Investigation

Vascular DiseaseLipid PeroxidationImmunologyHuman Atherosclerotic LesionsRedox Biology +16

Studies on the chlorinating activity of myeloperoxidase.

John Harrison, J. Schultz

Journal of Biological Chemistry

Advanced Oxidation ProcessChemical EngineeringBiosynthesisBioorganic ChemistryBiochemistry +13

3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.

Stanley L. Hazen, Jay W. Heinecke

Journal of Clinical Investigation

Lipid PeroxidationLow DensityReagent HoclRedox BiologyOxidative Stress +16

Presence of hypochlorite-modified proteins in human atherosclerotic lesions.

Linda Hazell, L. Arnold, Dave Flowers, +3

Journal of Clinical Investigation

Hocl AggregatesLipid PeroxidationImmunologyHypochlorite-modified ProteinsHocl-modified Proteins +14

Preparative and quantitative isolation of plasma lipoproteins: rapid, single discontinuous density gradient ultracentrifugation in a vertical rotor.

B H Chung, Tim Wilkinson, Jack C. Geer, +1

Journal of Lipid Research

Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro

Eugene A. Podrez, David Schmitt, Henry F. Hoff, +1

Journal of Clinical Investigation

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

Jay W. Heinecke, Wei Li, H.L. Daehnke, +1

Journal of Biological Chemistry

OxysterolBiochemistryMedicineHeme DegradationLipid Peroxidation +11

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.

Jay W. Heinecke, W. Li, Gordon A. Francis, +1

Journal of Clinical Investigation

Redox SignalingBiosynthesisBiochemistryOxidative Cross-linkingDityrosine Formation +13

Improved Measurement of Low-Density-Lipoprotein Susceptibility to Copper-Induced Oxidation: Application of a Short Procedure for Isolating Low-Density Lipoprotein

Henne A. Kleinveld, Heidi L.M. Hak-Lemmers, Anton F. H. Stalenhoef, +1

Clinical Chemistry

Low-density LipoproteinLipid PeroxidationRedox BiologyOxidative StressBioanalysis +15

Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein.

M.L. Savenkova, Dianne M. Mueller, Jay W. Heinecke

Journal of Biological Chemistry