Concepedia

Antibody to Hepatitis B Core Antigen and Risk for Hepatitis C–Related Hepatocellular Carcinoma

Kazuki Ikeda, Hiroyuki Marusawa, Yukio Osaki, Takefumi Nakamura, Naoto Kitajima, Yukitaka Yamashita, Masatoshi Kudo, Tosiya Sato, Tsutomu Chiba

Annals of Internal Medicine · 2007 · 134 citations · 43 references

DOI

Abstract

Anti-HBc-positive results on serologic testing are a marker of high risk for HCC among patients with HCV-related cirrhosis. Interferon therapy might be less effective in preventing HCC among patients with chronic hepatitis C who are anti-HBc-positive than in those with chronic hepatitis C who are anti-HBc-negative.

References

43

Interferon Therapy Reduces the Risk for Hepatocellular Carcinoma: National Surveillance Program of Cirrhotic and Noncirrhotic Patients with Chronic Hepatitis C in Japan

Haruhiko Yoshida, Yasushi Shiratori, Mitsuhiko Moriyama et al. · Annals of Internal Medicine · 1999 · 1.1K citations

World Medical Association Declaration of Helsinki

JAMA · 1997 · 1K citations

, , +8

The Continuing Increase in the Incidence of Hepatocellular Carcinoma in the United States: An Update

Hashem B. El‐Serag, Jessica A. Davila, Nancy J. Petersen et al. · Annals of Internal Medicine · 2003 · 943 citations · Full text

Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis

S. Nishiguchi, Tomoyuki Kuroki, Shinji Nakatani et al. · The Lancet · 1995 · 864 citations · Full text

, , +11

Occult Hepatitis B Virus Infection in Patients with Chronic Hepatitis C Liver Disease

Irene Cacciola, Teresa Pollicino, Giovanni Squadrito et al. · New England Journal of Medicine · 1999 · 663 citations · Full text