Concepedia

Mitochondrial calcium regulates rat liver regeneration through the modulation of apoptosis

Mateus T. Guerra, Emerson A. Fonseca, Flávia Medeiros Melo, Viviane A. Andrade, Carla Aguiar, Lídia M. Andrade, Ana Cristina N. Pinheiro, Marisa C. F. Casteluber, Rodrigo R. Resende, Mauro Cunha Xavier Pinto,

Hepatology · 2011 · 58 citations · 35 references

DOIFull text

Open access

Abstract

Together, these results reveal an essential role for Ca(mit)(2+) in hepatocyte proliferation and liver regeneration, which may be mediated by the regulation of apoptosis.

References

35

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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Experimental pathology of the liver

Gm. Higgins · Medical Entomology and Zoology · 1931 · 3.1K citations

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Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal

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Mitofusin 2 tethers endoplasmic reticulum to mitochondria

Olga Martins de Brito, Luca Scorrano · Nature · 2008 · 2.3K citations

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