Loss of Caveolae, Vascular Dysfunction, and Pulmonary Defects in Caveolin-1 Gene-Disrupted Mice

Marek Dráb, Paul Verkade, Marlies Elger, +10

Science

Lung InflammationNitric OxideGeneticsPulmonary DefectsCalcium Signaling +18

Targeted Disruption of Mouse EGF receptor: Effect of Genetic Background on Mutant Phenotype

David W. Threadgill, Andrzej A. Dlugosz, Laura A. Hansen, +11

Science

Genome-wide, large-scale production of mutant mice by ENU mutagenesis

Martin Hrabě de Angelis, Heinrich Flaswinkel, Helmut Fuchs, +33

Nature Genetics

Knockout MouseMutant MiceGeneticsGenetic EngineeringMedicine +2

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

William F. Dietrich

Cell

Knockout MouseGeneticsMin-induced Intestinal NeoplasiaGastroenterologyColorectal Cancer +6

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

Patrick M. Nolan, Jo Peters, Mark Strivens, +41

Nature Genetics

Knockout MouseTransgenic Mouse ModelsGeneticsPhenotype-driven Mutagenesis ProgrammeGene Characterization +9

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

Melina MacPhee, Kenneth P. Chepenik, Rebecca A. Liddell, +3

Cell

Signal TransductionSignaling PathwayApcmin-induced Intestinal NeoplasiaImmunologyGastroenterology +7

Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice.

SHOUICHI KADO, Hitoshi Funabashi, S Iwata, +6

PubMed

ImmunologyGastroenterologyPathologyTcrbeta-/- P53-/-Spontaneous Adenocarcinoma +14

Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia

Laurie Kurihara

Human Molecular Genetics