Some 3-Carboxamides of b-Carboline and Tetrahydro-b-carboline

Abstract

A s e r i e s of tetrahydra-6-carboline-3-carboxahidea IL-and D -s e r i e s ) was made by the i n t e r a c t i o n of the respective m i n e with the appropriate methyl tetrahydro-8-carboline-3-carboxylate.The B-carboline-3carboxanides were prepared by a similar route from methyl 8-carboline-3carboxylate or by aromatization of t h e respective tetrahydro-B-carbaline-3carboxamide.me diastereoners of N-E-butyl tetrahydra-8-carho1ina-Jcarhaxanide IL-and D-series) were separated by chromatography.m e s t u d i e s by Braestrup and co-workers i n 1979, which suggested