Acta Crystallographica Section C Crystal Structure Communications · 2000 · 23 citations · 6 references
Natural SciencesBiochemistryChemistryOrganic ChemistryStructural BiologySupramolecular ChemistryMacromolecular StructurePeptide Bond ChemistryPeptide ChemistryProtein StructureSecondary StructureSecondary Structure FormationBeta Turn ConformationPeptide Bond Geometry
The silaproline-containing dipeptide N-(3, 3-dimethyl-1-pivaloyl-1-aza-3-sila-5-cyclopentylcarbonyl)-L- alanine isopropylamide, C(17)H(33)N(3)O(3)Si, has two independent molecules in the asymmetric unit and each adopts a beta-II folded conformation, where the amide on the terminal C interacts intramolecularly with the pivaloyl O atom. The five-membered silaproline ring is C(beta)-puckered, an infrequent conformation for the homologous proline ring.
6