Health Affairs · 2014 · 58 citations · 16 references
PharmacyPharmaceutical PolicyPharmacy PracticeDrug DeliveryDrug Utilization ReviewPharmaceutical CareDrug Distribution SystemsMedication Administration SystemsPharmaceutical DistributionPrescription Drug PolicySpecialty Drug CoverageSpecialty Medication DispensingAccess To Specialty MedicationsHigh-cost Specialty MedicationsMedication Cost ManagementSpecialty Drug CostsSpecialty Drug TieringSpecialty Drug UtilizationSpecialty Pharmacy ReimbursementTiered Formularies
Spending on specialty medications, which represented a small proportion of US pharmacy spending at the beginning of this decade, is growing by more than 15 percent annually. It is expected to account for approximately half ($235 billion) of total annual pharmacy spending by 2018. Among the numerous reasons for the high cost of this heterogeneous group of medications are the increasing size of target patient populations, the high cost of drug development, and a complex and uncoordinated delivery system. In this article we describe the evolution of the specialty market, characterize the current state of specialty medication use, and articulate key challenges and potential solutions. Fully realizing the potential value of the expanding universe of specialty medications will require collaborative efforts to reduce waste and promote value. Those who prescribe, dispense, deliver, and pay for specialty medications will need to employ a combination of traditional and novel management approaches, such as prior authorization, step therapy, tiered formularies, administration at lower-cost sites, and the unique tools being developed for cancer medications.
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Bending the Cost Curve in Cancer Care
Thomas J. Smith, Bruce E. Hillner · New England Journal of Medicine · 2011 · 391 citations
Therapies for Active Rheumatoid Arthritis after Methotrexate Failure
James R. O’Dell, Ted R. Mikuls, Thomas H. Taylor et al. · New England Journal of Medicine · 2013 · 380 citations · Full text
William H. Shrank, Tuyen Hoang, Susan L. Ettner et al. · Archives of Internal Medicine · 2006 · 344 citations
Elena B. Elkin, Peter B. Bach · JAMA · 2010 · 156 citations · Full text