Impact of Nicotine Metabolism on Nicotine’s Pharmacological Effects and Behavioral Responses: Insights from a Cyp2a(4/5)bgs-Null Mouse

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

Yong Zhang, Meirong Huo, Jianping Zhou et al. · Computer Methods and Programs in Biomedicine · 2010 · 2K citations

Pharmacodynamic Data Analysis, Pharmacokinetic Modeling, Drug Resistance +8

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

William A. Corrigall, Keith B.J. Franklin, Kathleen M. Coen et al. · Psychopharmacology · 1992 · 830 citations

Tobacco Control, Psychoactive Drug, Neurophysiology +14

Drug-induced conditioned place preference and aversion in mice

Christopher L. Cunningham, Christina M. Gremel, Peter A. Groblewski · Nature Protocols · 2006 · 458 citations

Behavioral Sciences, Behavioral Neuroscience, Addiction +8

Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

Hiroshi Yamazaki, Kiyoshi Inoue, M Hashimoto et al. · Archives of Toxicology · 1999 · 235 citations

Molecular Pharmacology, Biochemistry, Medicine +11

Antinociceptive activity of narcotic agonist and partial agonist analgesics and other agents in the tail-immersion test in mice and rats

Robert D. E. Sewell · Neuropharmacology · 1976 · 231 citations

Tail-immersion Test, Partial Agonist Analgesics, Health Sciences +13