Concepedia

Randomized, double-blind, placebo-controlled trial of ezogabine (retigabine) in partial epilepsy

Jacqueline A. French, Bassel Abou‐Khalil, Robert Leroy, Elza Márcia Targas Yacubian, Paul Shin, Susan T. Hall, Harry H. Mansbach, Virinder Nohria

Neurology · 2011 · 181 citations · 31 references

DOI

Abstract

This study provides Class II evidence that EZG(RTG) 1,200 mg/day is effective as adjunctive therapy in adults with partial-onset seizures with or without secondary generalization.

References

31

Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies

Patrick Kwan, Alexis Arzimanoglou, Anne T. Berg et al. · Epilepsia · 2009 · 4.6K citations

The American Urological Association Symptom Index for Benign Prostatic Hyperplasia

Michael J. Barry, Floyd J. Fowler, Michael P. O’Leary et al. · The Journal of Urology · 1992 · 3.4K citations

, , +8

Efficacy and Safety of Oral Lacosamide as Adjunctive Therapy in Adults with Partial‐Onset Seizures

Elinor Ben‐Menachem, Victor Biton, Dalius Jatužis et al. · Epilepsia · 2007 · 476 citations

Activation of Expressed KCNQ Potassium Currents and Native Neuronal M-Type Potassium Currents by the Anti-Convulsant Drug Retigabine

L. Tatulian, Patrick Delmas, Fe C. Abogadie et al. · Journal of Neuroscience · 2001 · 401 citations · Full text

Retigabine, A Novel Anti-Convulsant, Enhances Activation of KCNQ2/Q3 Potassium Channels

Alan D. Wickenden, Weifeng Yu, Anrou Zou et al. · Molecular Pharmacology · 2000 · 318 citations