Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

Thorgeir E. Thorgeirsson, Frank Geller, Patrick Sulem et al. · Nature · 2008 · 1.5K citations

Tobacco Cessation, Tobacco Control, Tobacco Use +10

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Christopher I. Amos, Xifeng Wu, Peter Broderick et al. · Nature Genetics · 2008 · 1.3K citations · Full text

Genome-wide Association Study, Medicine, Genetics +9

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

Rayjean J. Hung, James McKay, Valérie Gaborieau et al. · Nature · 2008 · 1.3K citations · Full text

Tobacco Control, Lung Cancer Maps, Nicotine +10

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

Laura J. Bierut, Jerry A. Stitzel, Jen C. Wang et al. · American Journal of Psychiatry · 2008 · 637 citations · Full text

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

Wade H. Berrettini, Xin Yuan, Federica Tozzi et al. · Molecular Psychiatry · 2008 · 464 citations · Full text

Tobacco Control, Tobacco Use, Nicotine +4