Journal of Periodontology · 1992 · 31 citations · 18 references
DentistryMolecular BiologyOral BiologyMolecular VirologyOral MicrobiologyVirologyGingival BiologyGingival DiseaseOral InfectionsOral Viral InfectionsOral Viral MicrobiologyViral InfectionsHerpes Simplex Virus LatencyHost-microbe Interactions In GingivaImmunofluorescence AssaysImmunofluorescence DiagnosisImmunofluorescence StainingOral Herpes Simplex InfectionOral Herpesvirus BiologyOral Viral Diagnosis
The presence of herpes simplex virus (HSV) antigens was shown by immunofluorescence staining in 26 of 66 (39.3%) specimens of clinically healthy gingiva, but only one sample contained infectious virus. HSV DNA sequences were clearly identified in intact gingival cells by dot blot hybridization in one specimen, and a weak pattern in a second one. Both specimens harbored viral antigens. These findings of viral genome and protein expression suggest that the virus is present in the latent form in the gingiva.
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The purification of four strains of poxvirus
Wolfgang K. Joklik · Virology · 1962 · 550 citations
STUDIES OF THE NATURAL HISTORY OF HERPES SIMPLEX INFECTIONS
G. John Buddingh, David I. Schrum, James C. Lanier et al. · PEDIATRICS · 1953 · 272 citations