Matched-Control Retrospective Study of the Acute and Late Complications in Patients with Collagen Vascular Diseases Treated with Radiation Therapy

Abstract

This is the largest matched-control study thus far in the literature. In the comparison between the patients with CVD and the matched-control patients, there was no significant difference in the incidence of acute or late complication. However, there was a higher incidence of radiation complications in patients with scleroderma. Importantly, no fatal complication was noted in any of the patients with CVD.