Helvetica Chimica Acta · 2003 · 16 citations · 12 references
Optical MaterialsEngineeringNatural SciencesDiversity-oriented SynthesisLactone FormationFluorous SynthesisOrganic ChemistryNew SynthesisDirect AdditionChemistryHeterocycle ChemistryPharmacologyActive Amino AlcoholsBiomolecular Engineering
Abstract Optically active (perfluoroalkyl)‐oxazepin‐7‐ones were synthesized in two steps starting from ethyl perfluorobut‐2‐ynoate by direct addition of optically active amino alcohols via intermolecular Michael addition and lactone formation.
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