A New Synthesis of Optically Active 3‐Substituted (3<i>S</i>)‐3,4‐Dihydro‐5‐(perfluoroalkyl)‐2<i>H</i>‐[1,4]oxazepin‐7‐ones

Sébastien Richard, Gildas Prié, Alain Guignard, Jérôme Thibonnet, Jean‐Luc Parrain, Alain Duchêne, Mohamed Abarbri

Helvetica Chimica Acta · 2003 · 16 citations · 12 references

Concepts

Abstract

Abstract Optically active (perfluoroalkyl)‐oxazepin‐7‐ones were synthesized in two steps starting from ethyl perfluorobut‐2‐ynoate by direct addition of optically active amino alcohols via intermolecular Michael addition and lactone formation.

References

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