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Improved high-performance liquid chromatographic method for the simultaneous determination of caffeine and its N-demethylated metabolites in plasma using solid-phase extraction

N-demethylated MetabolitesGas ChromatographyMedicineBioanalysisAnalytical ChemistrySimultaneous DeterminationSolid-phase ExtractionLiquid ChromatographyMetabolomicsChromatographic AnalysisPharmacologyChromatographyDrug Analysis