Inclusion Body Myositis Associated With Sjogren's Syndrome

Abstract

• A patient with polymyositis had the pathological hallmarks of inclusion body myositis (IBM) as well as features that to our knowledge have never before been reported in IBM—an associated collagenvascular disease (Sjögren's syndrome) and tubuloreticular structures in capillary endothelial cells. The pathogenesis of IBM is unknown, but its coexistence with Sjögren's syndrome suggests that immune mechanisms may play a role in producing muscle damage.