Monoclonal antibodies against the structural proteins of viral haemorrhagic septicaemia virus isolates

Abstract

Abstract. Five VHSV isolates from different host species and Spanish geographical locations and three viral haemorrhagic septicaemia virus (VHSV) international reference serotypes (F 1 , F 2 and 23˙75) were studied by several characterized monoclonal antibodies (MAbs) including a neutralizing MAb to four structural proteins of VHSV. We report here the lack of reaction between anti‐M1 and some of the isolates of VHSV and the homogeneity of most of the isolates with respect to the MAbs tested. The reagents obtained will improve diagnostic tests which currently use polyclonal antibodies.