The Evaluation of Reno- and Hepato-Protective Effects of Huai-Shan-Yao (Rhizome Dioscoreae)

Abstract

Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.