Identification of unusual C–Cl⋯π contacts in 2-(alkylamino)-3-chloro-1,4-naphthoquinones: effect of N-substituents on crystal packing, fluorescence, redox and anti-microbial properties

Abstract

XRD study demonstrates the opening of unusual C–Cl⋯π synthon in 2-(alkylamino)-3-chloro-1,4-naphthoquinone. Notably, compound holding <italic>N</italic>-pyridylmethyl exhibits enhanced activity against <italic>S. aureus</italic> and proved to be more potent than ciprofloxacin.