Nickel‐Catalyzed Coupling of Aryl Bromides in the Presence of Alkyllithium Reagents

Abstract

Easy aryl couplings: In efforts to develop an improved catalytic method for transition-metal-catalyzed aryl coupling reactions, a one-pot, one-step, nickel-catalyzed coupling of aryl bromides aided by alkyllithium reagents is reported. By using catalytic amounts of nickel(II) and 0.5 equiv of alkyllithium, the homocoupling of various aryl bromides under mild conditions is accomplished in good yields (see scheme). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2111/2008/z801008_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.