In vivo gene amplification in non-cancerous cells: cholinesterase genes and oncogenes amplify in thrombocytopenia associated with lupus erythematosus

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

Life Sciences, Immunology, Internal Medicine +14

Instability of a 550-Base Pair DNA Segment and Abnormal Methylation in Fragile X Syndrome

I. Oberlé, F. Rousseau, Dominique Heitz et al. · Science · 1991 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +16

Mapping of DNA Instability at the Fragile X to a Trinucleotide Repeat Sequence P(CCG) <i>n</i>

Eric J. Kremer, Melanie Pritchard, Michael Lynch et al. · Science · 1991 · 923 citations

Life Sciences, Genetics, Molecular Genetics +11

Fragile X Genotype Characterized by an Unstable Region of DNA

Shuancang Yu, Melanie Pritchard, Eric J. Kremer et al. · Science · 1991 · 799 citations

Life Sciences, Genetics, Molecular Genetics +16

The role of clonal selection and somatic mutation in autoimmunity

Mark J. Shlomchik, Ann Marshak‐Rothstein, Claudia B. Wolfowicz et al. · Nature · 1987 · 706 citations

Life Sciences, Genetics, Immunology +14