S100A6 binds p53 and affects its activity

Structure of the negative regulatory domain of p53 bound to S100B(betabeta).

David J. Weber, Richard R. Rust, Donna M. Baldisseri · Nature Structural Biology · 2000 · 312 citations

Life Sciences, Cell Biology, Molecular Biology +9

Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100b-binding protein.

Jacques Baudier, Christian Delphin, Didier Grünwald et al. · Proceedings of the National Academy of Sciences · 1992 · 287 citations

Life Sciences, Molecular Biology, Oncology +17

Tumor Suppressor p53 Protein Is a New Target for the Metastasis-associated Mts1/S100A4 Protein

Mariam Grigorian, Susanne Andresen, Eugene Tulchinsky et al. · Journal of Biological Chemistry · 2001 · 283 citations · Full text

Medicine, Genetics, Oncology +11

Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor

Marı́a Rosario Fernández-Fernández, Dmitry B. Veprintsev, Alan R. Fersht · Proceedings of the National Academy of Sciences · 2005 · 170 citations

Life Sciences, Cell Biology, Molecular Biology +15

The Role of S100A6 in Pancreatic Cancer Development and Its Clinical Implication as a Diagnostic Marker and Therapeutic Target

Kenoki Ohuchida, Kazuhiro Mizumoto, Nami Ishikawa et al. · Clinical Cancer Research · 2005 · 168 citations

Medicine, Oncology, Pathology +17