Concepedia

Aberrant Expression of Mucin Core Proteins and O-Linked Glycans Associated with Progression of Pancreatic Cancer

Neeley Remmers, Judy M. Anderson, Erin M. Linde, Dominick J. DiMaio, Audrey J. Lazenby, Hans H. Wandall, Ulla Mandel, Henrik Clausen, Fang Yu, Michael A. Hollingsworth

Clinical Cancer Research · 2013 · 159 citations · 53 references

DOIFull text

Open access

Abstract

There are significant alterations in mucin expression and posttranslational processing during progression of pancreatic cancer from early lesions to metastasis. The results are presented in the context of how mucins influence the biology of tumor cells and their microenvironment during progression of pancreatic cancer.

References

53

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

Yoav Benjamini, Yosef Hochberg · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1995 · 105.5K citations

, , +21

Human Tumor Antigens Tn and Sialyl Tn Arise from Mutations in <i>Cosmc</i>

Tongzhong Ju, Grainger S. Lanneau, Tripti Gautam et al. · Cancer Research · 2008 · 289 citations

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

Lopamudra Das Roy, Mahnaz Sahraei, Durai B. Subramani et al. · Oncogene · 2010 · 265 citations · Full text

, , +9

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance

Anne Louise Tølbøll Sørensen, Celso A. Reis, Mads A. Tarp et al. · Glycobiology · 2005 · 257 citations · Full text

, , +19

Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas

Grace Kim, Han‐Ik Bae, Hee–Ug Park et al. · Gastroenterology · 2002 · 250 citations

, , +9