MOLECULAR WEIGHT AND HOMOGENEITY OF CRYSTALLINE BOTULINUS A TOXIN

Frank W. Putnam, Carl Lamanna, D. G. Sharp

Journal of Biological Chemistry · 1946 · 47 citations · 0 references

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Abstract

A TOXINThe isolation of Clostridium botulinurn type A toxin has been reported.1~2This crystalline toxin, the most potent known, contains about 220 X lo6 mouse LD50 per mg. of nitrogen.'In the equivalence zone both toxin and antitoxin are completely precipitated.0 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6:Distance from Axis of Rotation in Cm.