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Brain anatomy in non-affected parents of autistic probands: a MRI study

DOI

29

Citations

0

References

2005

Year

S. J. M. C. Palmen, Hilleke E. Hulshoff Pol, Chantal Kemner, Hugo G. Schnack, Margriet M. Sitskoorn, Melanie C.M. Appels, René S. Kahn, Hermán van Engeland
Psychological Medicine

Abstract

The present sample of biological, non-affected parents of autistic probands did not show brain enlargements. As the intracranium is not enlarged, it is unlikely that the brain volumes of the parents of autistic probands have originally been enlarged and have been normalized. Thus, increased brain volume in autism might be caused by the interaction of paternal and maternal genes, possibly with an additional effect of environmental factors, or increased brain volumes might reflect phenotypes of autism.