Hepatocellular Carcinoma: Hepatocyte-selective Enhancement at Gadoxetic Acid–enhanced MR Imaging—Correlation with Expression of Sinusoidal and Canalicular Transporters and Bile Accumulation

Abstract

High hepatocyte-selective enhancement is induced by expression patterns of transporters, which may result in accumulation of gadoxetic acid in cytoplasm of tumor cells or in lumina of pseudoglands. An HCC with gadoxetic acid enhancement is characterized by bile accumulation in tumors.