DNA FLOW CYTOMETRY IN PRIMARY BREAST CARCINOMA

Abstract

DNA Flow cytometric values were recorded in 66 primary breast carcinomas. Twenty-six tumors were found to be diploid whereas 40 were non-diploid. About 10% of the cells belonged to the S-phase fraction. Non-diploid tumors had significantly larger S-cell fractions (greater than 10%) than diploid ones. High tumor ploidy correlated positively with high clinical stage (stage I versus stage greater than or equal to II) and with high histological grade but was unrelated to estrogen-receptor content and menopausal status.