Sildenafil prevents mortality and reduces hippocampal damage after permanent, stepwise, 4-vessel occlusion in rats

Phosphodiesterase-5 Inhibitor Sildenafil Preconditions Adult Cardiac Myocytes against Necrosis and Apoptosis

Anindita Das, Lei Xi, Rakesh C. Kukreja · Journal of Biological Chemistry · 2005 · 333 citations · Full text

Medicine, Cardiology, Pharmacology +14

Long-Term Use of Sildenafil in the Therapeutic Management of Heart Failure

Marco Guazzi, Michele Samaja, Ross Arena et al. · Journal of the American College of Cardiology · 2007 · 321 citations · Full text

Pharmacy, Cardiology, Pharmacotherapy +13

Circle of Willis Atherosclerosis Is a Risk Factor for Sporadic Alzheimer’s Disease

Alex E. Roher, Chera L. Esh, Tyler A. Kokjohn et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2003 · 280 citations

Medicine, Neurology, Neuroscience +17

Phosphodiesterase Type 5 as a Target for the Treatment of Hypoxia-Induced Pulmonary Hypertension

Abdelkrim Sebkhi, Julian Strange, Steven C. Phillips et al. · Circulation · 2003 · 256 citations

Medicine, Pharmacology, Pharmacotherapy +16

Neurobehavioral deficit due to ischemic brain damage limited to half of the CA1 sector of the hippocampus

ML Jensen, IQ Whishaw · Journal of Neuroscience · 1989 · 234 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17