Electrical Stimulation for Epilepsy: Stimulation of Hippocampal Foci

Francisco Velasco, Marcos Velasco, Ana Luisa Velasco, Diana Menez, Luísa Rocha

Stereotactic and Functional Neurosurgery · 2001 · 107 citations · 3 references

Concepts

Abstract

Subacute and chronic continuous electrical stimulation at the epileptic focus in the hippocampus or parahippocampal cortex at 130 Hz, 0.21-1.0 ms, 2.5-3.5 V (about 200-300 microA) induces a decrease in focal EEG epileptic interictal activity and also in the occurrence of clinical seizures. This may represent an alternative for the treatment of temporal lobe seizures originated in bilateral independent temporal lobe foci or occurring in patients where one is uncertain whether memory deficit might result from ablative procedures.

References

3