Noncommercial Fabrication of Antibiotic-impregnated Polymethylmethacrylate Beads

Arthur B. Flick, James C. Herbert, John A. Goodell, Thomas Kristiansen

Clinical Orthopaedics and Related Research · 1987 · 33 citations · 0 references

Concepts

Abstract

Antibiotic-impregnated polymethylmethacrylate (PMMA) beads were fabricated by means of injections in specially designed molds to produce small and large beads. In vitro concentrates from these beads for 30 days were found to release tobramycin in an exponential function.