Idiopathic Ventricular Septal Hypertrophy Causing Muscular Subaortic Stenosis

Abstract

The clinical, hemodynamic, angiographic and, where available, surgical and postmortem findings of 10 cases of muscular subaortic stenosis have been reviewed and, from the evidence at hand, it would appear that the majority of these cases had as the basis for the stenosis, idiopathic ventricular septal hypertrophy (asymmetrical hypertrophy of the heart). 3 This septal muscle mass leads to obstruction of the right as well as the left ventricular outflow tract, in addition to impeding diastolic ventricular filling as a result of low ventricular compliance. These features give rise to a unique clinical, hemodynamic, and angiographic picture.