Pharmacokinetic characteristics of vincristine sulfate liposomes in patients with advanced solid tumors

Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models

MS Webb, TO Harasym, Dana Masin et al. · British Journal of Cancer · 1995 · 240 citations · Full text

Tumor Biology, Medicine, Therapeutic Properties +8

Inhibition of tubulin-microtubule polymerization by drugs of the Vinca alkaloid class.

Richard J. Owellen, Carol Hartke, Ruth M. Dickerson et al. · PubMed · 1976 · 206 citations

Pharmaceutical Science, Tubulin Concentration, Pharmacotherapy +17

Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention

Igor V. Zhigaltsev, Norbert Maurer, Quet-Fah Akhong et al. · Journal of Controlled Release · 2005 · 187 citations

Lipid Preparation, Medicinal Chemistry, Pharmaceutical Science +10

Vincristine sulfate liposomes injection (Marqibo) in heavily pretreated patients with refractory aggressive non‐Hodgkin lymphoma

Maria Alma Rodriguez, Robert Pytlík, Tomáš Kozák et al. · Cancer · 2009 · 140 citations · Full text

Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing P388 tumors.

Nancy L. Boman, Dana Masin, L.D. Mayer et al. · PubMed · 1994 · 126 citations

Pharmaceutical Science, Drug Targeting, P388 Tumors +15