Concepedia

cAMP Response Element Binding Protein Is Expressed and Phosphorylated in the Human Heart

Frank Müller, Peter Boknı́k, Andreas Horst, Jörg Knapp, Bettina Linck, Wilhelm Schmitz, Ute Vahlensieck, Michael Böhm, Mario C. Deng, Hans H. Scheld

Circulation · 1995 · 50 citations · 17 references

DOI

Abstract

We conclude that in the failing and nonfailing human heart, CREB is expressed on the protein and mRNA levels and that CREB is phosphorylated and able to bind to CREs, indicating a functional role of CREB in the human heart.

References

17

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

, , +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

, , +7

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

, , +19

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

Martin Ungerer, Michael Böhm, John S. Elce et al. · Circulation · 1993 · 875 citations · Full text

Regulation of CREB Phosphorylation in the Suprachiasmatic Nucleus by Light and a Circadian Clock

David D. Ginty, Jon M. Kornhauser, Margaret A. Thompson et al. · Science · 1993 · 823 citations

, , +27