Proliferative Patterns of Rectal Mucosa as Predictors of Advanced Colonic Neoplasms in Routinely Processed Rectal Biopsies

Abstract

Our data suggest that the evaluation of the upward expansion of the rectal crypt proliferative zone in routinely processed rectal biopsies of apparently normal mucosa appears to predict the presence of advanced colonic neoplasms. These preliminary results should be confirmed in larger studies.