Archives of Disease in Childhood · 1985 · 39 citations · 6 references
Life SciencesGeneticsGenetic CounselingHuman GeneticsMedical GeneticsGenetic DisordersGenetic SyndromesMendelian DisordersSingle-gene DisordersTwin StudiesBeckwith-wiedemann SyndromeDizygotic TwinsGenetic Correlation In Twin StudiesMonozygotic TwinsMultifactorial Inheritance ModelsSingle-gene InheritanceTwin DesignsTwin Pair Discordance
A pair of monozygotic twins discordant for Wiedemann-Beckwith syndrome is described. The probability of monozygosity is 0.995. This observation suggests that the syndrome is unlikely to be under single gene control and genetic counselling should be based on multifactorial inheritance.
6
Monozygotic twinning and structural defects
Albert Schinzel, David W. Smith, James R. Miller · The Journal of Pediatrics · 1979 · 530 citations
Localization of insulin-like growth factor genes to human chromosomes 11 and 12
James V. Tricoli, Leslie B. Rall, James Scott et al. · Nature · 1984 · 184 citations
[FAMILIAL MALFORMATION COMPLEX WITH UMBILICAL HERNIA AND MACROGLOSSIA--A "NEW SYNDROME"?].
Wiedemann Hr · PubMed · 1964 · 161 citations
Medicine, Obstetrics, Pediatrics +12
THE BECKWITH-WIEDEMANN SYNDROME
Giorgio Filippi, Victor A. McKusick · Medicine · 1970 · 117 citations
Medicine, Genetics, Pediatrics +17