Circulation · 1952 · 10 citations · 5 references
MedicineCardiologyPharmacologyCardiovascular PharmacotherapyClinical CardiologyPharmaceutical FormulationCardiac MedicationsCardiac PharmacotherapyCardiovascular PharmacologyVasoactive Drug TherapyVasoactive MedicationsVasodilator TherapyCardiac GlycosidesImpuritiesSystemic Vasodilator TherapyVasoactive Drug AdministrationVasoactive Drug UseVasodilator Pharmacology
The high incidence of unpleasant side effects following the use of crude preparations of khellin in the treatment of angina pectoris has limited its clinical use. It was felt that if this vasodilator drug were prepared free of resins, chromones and other plant impurities, it might then be used more extensively in the treatment of coronary insufficiency. Currently, a crystalline preparation of high purity has become available. A series of patients with angina pectoris were studied using this preparation. A Starr ballistocardiograph was interjected into our study in an attempt to obtain objective evidence of any effect this drug might have on the mechanical action of the heart.
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Isaac Starr, Orville Horwitz, Robert L. Mayock et al. · Circulation · 1950 · 80 citations
Nursing, Cardiology, Physiology +11
AMMI VISNAGA IN THE TREATMENT OF THE ANGINAL SYNDROME
G. V. Anrep, G. S. Barsoum, M.R. Kenawy et al. · Heart · 1946 · 55 citations · Full text
KHELLIN IN THE TREATMENT OF ANGINA OF EFFORT
H. A. Dewar, T. A. Grimson · Heart · 1950 · 39 citations · Full text
Medicine, Cardiology, Pharmacology +16