Ubiquitinated pathological lesions in frontotemporal lobar degeneration contain the TAR DNA-binding protein, TDP-43

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Manuela Neumann, Deepak M. Sampathu, Linda K. Kwong et al. · Science · 2006 · 6.6K citations

Life Sciences, Neurology, Neuroscience +14

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama et al. · Biochemical and Biophysical Research Communications · 2006 · 2.8K citations

Life Sciences, Neurology, Neuroscience +11

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

Matt Baker, Ian R. Mackenzie, Stuart Pickering‐Brown et al. · Nature · 2006 · 2.1K citations

Life Sciences, Genetics, Neurology +12

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

Marc Cruts, Ilse Gijselinck, Julie van der Zee et al. · Nature · 2006 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +11

Clinical and Pathological Diagnosis of Frontotemporal Dementia

Guy M. McKhann · Archives of Neurology · 2001 · 1.5K citations

Medicine, Neurology, Psychiatry +12