Inherited risk factors for thrombophilia in children with nephrotic syndrome

Mutation in blood coagulation factor V associated with resistance to activated protein C

Rogier M. Bertina, Bobby P. C. Koeleman, Ted Koster et al. · Nature · 1994 · 3.8K citations

Genetics, Pathogenesis, Hematology +6

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis

SR Poort, FR Rosendaal, PH Reitsma et al. · Blood · 1996 · 3.1K citations · Full text

Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C.

Björn Dahlbäck, Martin Carlsson, Peter J. Svensson · Proceedings of the National Academy of Sciences · 1993 · 2K citations · Full text

Immunology, Genetic Epidemiology, Pathology +21

The Mutation Ala677→Val in the Methylene Tetrahydrofolate Reductase Gene: A Risk Factor for Arterial Disease and Venous Thrombosis

Valder R. Arruda, Paula M. von Zuben, Luiz C Chiaparini et al. · Thrombosis and Haemostasis · 1997 · 305 citations

Prevalence of the Prothrombin Gene Variant (nt20210A) in Venous Thrombosis and Arterial Disease

Valder R. Arruda, Joyce Maria Annichino‐Bizzacchi, Marilda de Souza Gonçalves et al. · Thrombosis and Haemostasis · 1997 · 168 citations

Hypertension, Vascular Disease, Genetics +27