Totally stereocontrolled synthesis of α,β-diamino acids by addition of Grignard reagents to nitrones derived from l-serine

Development and use of quantum mechanical molecular models. 76. AM1: a new general purpose quantum mechanical molecular model

Michael J. S. Dewar, Eve G. Zoebisch, Eamonn F. Healy et al. · Journal of the American Chemical Society · 1985 · 13.1K citations

Natural Sciences, Chemistry, Physics +10

Rapid chromatographic technique for preparative separations with moderate resolution

W. Clark Still, Michaël Kahn, Abhijit Mitra · The Journal of Organic Chemistry · 1978 · 5.8K citations

Pharmacy, Chemistry, Analytical Chemistry +8

Cyanohydridoborate anion as a selective reducing agent

Richard F. Borch, Mark D. Bernstein, H. D. Durst · Journal of the American Chemical Society · 1971 · 1.8K citations

Natural Sciences, Chemistry, Analytical Chemistry +5

Theory and Modeling of Stereoselective Organic Reactions

K. N. Houk, Michael N. Paddon‐Row, Nelson G. Rondan et al. · Science · 1986 · 314 citations

Natural Sciences, Chemistry, Computational Chemistry +15

Erythro-Selective aldol-type reaction of N-sulfonylaldimines with methyl isocyanoacetate catalyzed by gold(I)

Tamio Hayashi, Eiji Kishi, Vadim A. Soloshonok et al. · Tetrahedron Letters · 1996 · 102 citations

Natural Sciences, Biochemistry, Chemistry +7