Chemistry of <i>ent</i>-Halimic Acid: Synthesis of [4.3.3]Propellanes

Abstract

ent-Halimic acid was used as the starting material for an efficient synthesis of a series of tetranor derivatives, functionalized at C-18. These compounds could be used to synthesise [4.3.3]propellanes, oxides and lactones similar to ambreinolide, all of which may be of interest to the perfume industry.