Concepedia

Chronic treatment of aged mice with L-deprenyl produces marked striatal MAO-B inhibition but no beneficial effects on survival, motor performance, or nigral lipofuscin accumulation

Donald K. Ingram, Harvey L. Wiener, Mark E. Chachichi, Jeffrey M. Long, John Hengemihle, Madi Gupta

Neurobiology of Aging · 1993 · 31 citations · 50 references

References

50

Aging: A Theory Based on Free Radical and Radiation Chemistry

Denham Harman · Journal of Gerontology · 1956 · 8.5K citations

Natural Sciences, Chemistry, Aging +16

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

Richard E. Heikkila, Lawrence Manzino, Felicitas S. Cabbat et al. · Nature · 1984 · 1K citations

Medicine, Neuroscience, Pharmacology +14

Effect of Deprenyl on the Progression of Disability in Early Parkinson's Disease

New England Journal of Medicine · 1989 · 919 citations

Medicine, Neurology, Pharmacology +14

Increased life expectancy resulting from addition of l-deprenyl to Madopar� treatment in Parkinson's disease: A longterm study

W Birkmayer, J. Knoll, Peter Riederer et al. · Journal of Neural Transmission · 1985 · 436 citations

Medicine, Neurology, Pharmacology +10

The potentiation of the anti akinetic effect after L-Dopa treatment by an inhibitor of Mao-B, deprenil

W Birkmayer, Peter Riederer, Moussa B. H. Youdim et al. · Journal of Neural Transmission · 1975 · 362 citations

Medicine, Pharmacology, Pharmacotherapy +11