Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

Abstract

Oral carnosine treatment protects retinal capillary cells in experimental diabetic retinopathy, independent of its biochemical function. The vasoprotective effect of carnosine might be mediated by the induction of protective Hsp27 in activated glial cells and normalization of hyperglycemia-induced Ang-2.