Ser1333 phosphorylation indicates ROCKI activation

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

Anne J. Ridley, Alan Hall · Cell · 1992 · 4.5K citations

Mechanobiology, Focal Adhesions, Actin Stress Fibers +14

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

Kazushi Kimura, Masaaki Ito, Mutsuki Amano et al. · Science · 1996 · 2.9K citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

Mutsuki Amano, Masaaki Ito, Kazushi Kimura et al. · Journal of Biological Chemistry · 1996 · 2K citations · Full text

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

Magdalena Chrzanowska‐Wodnicka, Keith Burridge · The Journal of Cell Biology · 1996 · 1.7K citations

Cell Adhesion, Activated Rhoa, Cytoskeleton +25

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

Takeshi Matsui, Mutsuki Amano, Takahisa Yamamoto et al. · The EMBO Journal · 1996 · 1.1K citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +10