Flavones are inhibitors of HIV-1 proteinase

Conserved Folding in Retroviral Proteases: Crystal Structure of Synthetic HIV-1 Protease

Alexander Wlodawer, Maria Miller, Mariusz Jaskólski et al. · Science · 1989 · 1.2K citations

Crystal Structure, Protein Assembly, Molecular Biology +23

Structure of Complex of Synthetic HIV-1 Protease with a Substrate-Based Inhibitor at 2.3 Å Resolution

Maria Miller, Jens Schneider, Bangalore K. Sathyanarayana et al. · Science · 1989 · 687 citations

Design, Activity, and 2.8 Å Crystal Structure of a <i>C</i> ₂ Symmetric Inhibitor Complexed to HIV-1 Protease

John W. Erickson, David J. Neidhart, John H. VanDrie et al. · Science · 1990 · 528 citations · Full text

X-ray analysis of HIV-1 proteinase at 2.7 Å resolution confirms structural homology among retroviral enzymes

Risto Lapatto, T. Blundell, Andrew M. Hemmings et al. · Nature · 1989 · 454 citations

Virus Structure, Viral Replication, Biochemistry +12

Enzymatic activity of a synthetic 99 residue protein corresponding to the putative HIV-1 protease

Jens Schneider, Stephen B. H. Kent · Cell · 1988 · 234 citations

Protein Chemistry, Synthetic 99, Protein Assembly +10