Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes

Methods in Enzymology , Vol

S P Colowick, M D Joshi, Jagannathan et al. · 1966 · 26.2K citations

Biosynthesis, Engineering, Cellular Enzymology +5

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Hepatology, Biochemistry, Carbon Monoxide-binding Pigment +9

Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats

Norman E. Sládek, Gilbert J. Mannering · Biochemical and Biophysical Research Communications · 1966 · 415 citations

Hepatology, Biochemistry, New P-450 Hemoprotein +10

Reconstituted Liver Microsomal Enzyme System That Hydroxylates Drugs, Other Foreign Compounds, and Endogenous Substrates

Anthony Y.H. Lu, R. Kuntzman, Susan West et al. · Journal of Biological Chemistry · 1972 · 354 citations · Full text

Reductase Fractions, Metabolomic Profiling, Molecular Pharmacology +20

Determination of drug metabolizing enzymes in needle biopsies of human liver

B. Schoene, R. Fleischmann, H. Remmer et al. · European Journal of Clinical Pharmacology · 1972 · 330 citations

Needle Biopsies, Bioanalysis, Drug Test +17