Concepedia

Anticonvulsant activity of the NMDA antagonists, d(−)4-(3-phosphonopropyl)piperazine-2-carboxylic acid (D-CPP) and d(−)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent and a primate model of reflex epilepsy

Smita S. Patel, Astrid G. Chapman, Joanne L. Graham, Brian S. Meldrum, P.A. Frey

Epilepsy Research · 1990 · 90 citations · 11 references

DOI

Concepts

References

11

A SIMPLIFIED METHOD OF EVALUATING DOSE-EFFECT EXPERIMENTS

J.T. LITCHFIELD, Frank Wilcoxon · Journal of Pharmacology and Experimental Therapeutics · 1949 · 7.3K citations

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Richard Morris, Eric Anderson, Gary Lynch et al. · Nature · 1986 · 3.6K citations

, , +7

Anticonvulsant Action of Excitatory Amino Acid Antagonists

M. J. Croucher, J.F. Collins, B.S. Meldrum · Science · 1982 · 693 citations

, , +16

CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]d-AP5 binding sites on brain membranes and anticonvulsant activity

J. Davies, Richard H. Evans, Paul L. Herrling et al. · Brain Research · 1986 · 309 citations

, , +13

CPP, a selective N-methyl-D-aspartate (NMDA)-type receptor antagonist: characterization in vitro and in vivo.

John Lehmann, Jennifer Schneider, Stephen E. McPherson et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 238 citations