Concepedia

Glucose metabolism parameters during an oral glucose tolerance test in patients with autosomal dominant polycystic kidney disease

Maria Pietrzak-Nowacka, Krzysztof Safranow, Elżbieta Byra, Monika Nowosiad, Małgorzata Marchelek‐Myśliwiec, Kazimierz Ciechanowski

Scandinavian Journal of Clinical and Laboratory Investigation · 2010 · 20 citations · 25 references

DOI

Abstract

Presence of ADPKD in patients with normal kidney function is associated with impaired beta cell function after an oral glucose load, without a significant decrease in insulin sensitivity.

References

25

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

R. A. DeFronzo, J. D. Tobin, R Andres · American Journal of Physiology-Endocrinology and Metabolism · 1979 · 7.4K citations

, , +18

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

Masafumi Matsuda, Ralph A. DeFronzo · Diabetes Care · 1999 · 5.5K citations

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose.

Richard N. Bergman, Lawrence S. Phillips, Claudio Cobelli · Journal of Clinical Investigation · 1981 · 1.6K citations · Full text

, , +17

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16

The European Polycystic Kidney Dise · Cell · 1994 · 896 citations · Full text

, , +10

Contributions of β-Cell Dysfunction and Insulin Resistance to the Pathogenesis of Impaired Glucose Tolerance and Impaired Fasting Glucose

Muhammad Abdul-Ghani, Devjit Tripathy, Ralph A. DeFronzo · Diabetes Care · 2006 · 731 citations · Full text

, , +20