Androgens inhibit the proliferation of a variant of the human prostate cancer cell line LNCaP

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

Michael C. Alley, Dominic A. Scudiero, Anne Monks et al. · PubMed · 1988 · 3.1K citations

Medicine, Oncology, Pharmacology +14

LNCaP model of human prostatic carcinoma.

Julius S. Horoszewicz, Susan S. Leong, Elzbieta Kawinski et al. · PubMed · 1983 · 1.8K citations

Medicine, Cancer Biology, Oncology +15

A mutation in the ligand binding domain of the androgen receptor of human INCaP cells affects steroid binding characteristics and response to anti-androgens

Jos Veldscholte, C. Ris-Stalpers, George G. J. M. Kuiper et al. · Biochemical and Biophysical Research Communications · 1990 · 945 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +14

Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

Dennis B. Lubahn, T. R. Brown, J A Simental et al. · Proceedings of the National Academy of Sciences · 1989 · 447 citations · Full text

Medicine, Genetics, Molecular Genetics +17